If you’re preparing for your USMLE Step 2 CK exam, you may be overwhelmed by all the topics you have to prepare for. It can feel like a small, vital step on a long road to your goal of becoming a doctor. The best way to prepare for these exams is by getting really comfortable with practice questions. We’ve chosen 4 highly rated questions from the BoardVitals USMLE Step 2 CK Practice Question Bank. Can you answer them correctly?
How did you do? Whether you aced them all or missed a few, you still can use more practice.
The USMLE Step 2 CK exam lasts approximately nine hours and consists of sixteen 30-minute blocks. In 2025, the pass rate for Step 2 was 97% among all test takers. According to the USMLE Step 2CK Content Outline, the topics covered on the exam are broken down as follows:
Table 1: Step 2 CK Test Specifications
- Nutrition: 15–20%
- Social Sciences: Legal/Ethical Issues & Professionalism/Systems-based Practice & Patient Safety: 10-15%
- Renal & Urinary System & Reproductive Systems: 7–13%
- Cardiovascular System: 6–12%
- Musculoskeletal System/Skin & Subcutaneous Tissue: 6–12%
- Behavioral Health: 5–10%
- Blood & Lymphoreticular/Immune Systems: 5-10%
- Gastrointestinal System: 5–10%
- Nervous System & Special Senses: 5–10%
- Respiratory System: 5–10%
- Multisystem Processes & Disorders: 4–8%
- Endocrine System: 3–7%
- Pregnancy, Childbirth & the Puerperium: 3–7%
- Biostatistics & Epidemiology/Population Health/Interpretation of Medical Literature: 3–5%
- Human Development: 2–4%
Table 2: Step 2 CK Physician Task/Competency Specifications
- Patient Care: Diagnosis 16–20%
- Patient Care: Laboratory/Diagnostic Studies 13–17%
- Patient Care: Mixed Management 12–16%
- Patient Care: Pharmacotherapy 8–12%
- Patient Care: Clinical Interventions 6–10%
- Patient Care: Health Maintenance/Disease Prevention 5–10%
- Patient Care: Prognosis/Outcome 5–9%
- Systems-Based Practice & Patient Safety 5–7%
- Professionalism 5–7%
- Practice-Based Learning & Improvement 3–5%
Table 3: Step 2 CK Clinical Science Specifications
- Medicine: 55–65%
- Pediatrics: 17–27%
- Obstetrics & Gynecology: 10–20%
- Psychiatry: 10–15%
- Surgery: 5–15%
BoardVitals USMLE Step 2 CK Practice Question Bank has more than 1,400 questions targeted to the USMLE Step 2 CK Board Exam. Click here for a free trial, and save 10% when you use promo code QUIZ10at checkout..
