Try These NAPLEX Practice Questions

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These are selected free practice questions from the BoardVitals NAPLEX question bank.

Sample NAPLEX Exam Questions

Question 1. Infectious Disease QID 36118

A doctor has diagnosed a patient with impetigo on his neck (see image) and is consulting you to determine which common organisms should be covered by antimicrobial therapy. Which two organisms would most likely be suspected? (Select two)

imp_neck_img_setsrtgkvn.jpg (450×599)

A. Staphylococcus aureus
B. Pseudomonas aeruginosa
C. Klebsiella pneumoniae
D. Clostridium difficile
E. Streptococcus pyogenes

Answer: A. Staphylococcus aureus and E. Streptococcus pyogenes.


Streptococcus pyogenes and Staphylococcus aureus are the two most common organisms that would be found in cultures of impetigo, a skin infection. Impetigo is a highly contagious bacterial skin infection most common among pre-school children on the face. Mild cases may be treated with topical ointments such as mupirocin and more severe cases require oral antibiotics, such as dicloxacillin, flucloxacillin or erythromycin.

Pseudomonas and Klebsiella are both Gram negative aerobic bacteria and Clostridium difficile is a gram positive anaerobe.

Reference: Antibiotics Simplified 2nd Edition By Åsa Thörn (Own work) [GFDL ( or CC BY-SA 3.0 (], via Wikimedia Commons

Question 2. Dermatology QID 34344

Which of the following is a topical retinoid is used in the treatment of psoriasis?

A. Anthralin
B. Calcipotriene
C. Acitretin
D. Adapalene
E. Allantoin

Answer: D. Adapalene.


Retinoids (such as tretinoin, adapalene, tazarotene and alitretinoin) are a class of medications derived from vitamin A that are used to treat a variety of skin conditions, including acne, aging skin and psoriasis.

Reference: CN2015

How did you do? If you’d like more tools to help prepare for the pharmacist’s test, learn how to break down a NAPLEX exam question or how to prepare for the pharmaceutical calculations on the NAPLEX.

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