NPLEX Part 1 Question Bank for the Naturopathic Licensing Exam

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“Each case is not only completely reflective of the actual exam, but provides you with a detailed description of why the selected answer is correct and why the distractors are incorrect. There is no better way to simulate the NPLEX exam or to test your current knowledge level. This is a great resource in helping you prepare for NPLEX.”

Dr. Chris Habib
ND Naturopathic Doctor and Instructor Creator of

gold key Key Board Review Features


NPLEX Part 1 Board Review Topics Covered:

  • Musculoskeletal System
  • Cardiovascular System
  • Gastrointestinal System
  • Reproductive System
  • Endocrine System
  • Hematopoietic System and Coagulation
  • Immunological System
  • Integumentary System
  • Neurological System
  • Pulmonary System and Upper Respiratory Tract
  • Urinary System

About the NPLEX Exam Part 1- Biomedical Science Examination (BSE)

The NPLEX Part 1 - BSE is case-based, meaning that the examination consists of clinical summaries followed by several questions referring to the patient’s case. However, the clinical summary is very brief on the NPLEX Part 1, since it does not require clinical training. Therefore all items relate to the biomedical foundation for the patient’s condition, not the diagnosis or treatment.

What is covered on the NPLEX Part 1 Exam?

According to the NABNE Exam Overview, the following topics will be on the exam:

Structure / Function

  • Anatomy
  • Physiology
  • Biochemistry & Genetics

Disease / Dysfunction

  • Microbiology & Immunology
  • Pathology

How long is the NPLEX Part 1 Exam?

NPLEX Part 1 questions are presented in a multiple-choice, single-answer format. NPLEX Part 1 - BSE is a cohesive examination that consists of 200 items. The examination is administered in two sessions (morning and afternoon) of 2½ hours each.

Tips and Advice for the NPLEX Part 1 Exam

Anatomy and physiology are by far the hardest sections of the NPLEX Part 1 exam and statistically where most students fail. However, the questions found within the pathology and microbiology sections are more straightforward and contain the highest pass rates when compared to the other portions of the exam. According to Bastyr University, the average pass percentile for the Comprehensive Mastery portion of the NPLEX Part 1 is 74%.

Those who’ve taken NPLEX Part 1 - BSE state that preparing for the exam should not be a stressful endeavor, as long as you’re committed to begin studying a few months in advance. Furthermore, adhering to a strict study schedule, maximizing good time management, and brushing up on anatomy, microbiology, and physiology are keys to success. These topics are all covered in the BoardVitals NPLEX Part 1 question bank to help you focus on the right material for the exam.